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Re: SAMe, selenium, tyrosine, DHEA, etc. » JLx

Posted by DSCH on November 21, 2003, at 11:25:36

In reply to Re: SAMe, selenium, tyrosine, DHEA, etc. » tealady, posted by JLx on November 21, 2003, at 10:10:32

> I've tried SAMe a couple times, the second time doubling the dose from the first time. From 400 mg to 800 mg I believe it was. The "more" was better, but then after 2 months, I sunk back down into depression and no energy again. This was prior to magnesium supplementation.

Perhaps you exceeded your ability to convert homocystiene back into methionine and the homocystiene began to build up. SAM-e shouldn't have the effect of 'consuming' magnesium I think.

> In my current everything-but-the-kitchen-sink trial, I had some SAMe left over from that prior time and took that along with all the amino acid experimentation (and magnesium) and really noticed it when I ran out. Less good mood, less energy. Hence my experimentation with TMG and methionine now to try to duplicate that result.
>
> The increased TMG actually feels BETTER than the SAMe...so far anyway. It's only been just this week that I've stepped up to approx. 800 mg 3x/day.

That's great! :-)

I'm giving 2000 mg of TMG tid a try. Also boosting my lecithin and fish oil too and returning to tid with my multi (recommended bid). The only things I'm not raising now are minerals (Ca and Mg) and the grape seed extract. I'm doing this because I've fallen back into lethargy somewhat, though my head has reamined pretty clear. I believe this is likely at least partly due to being laid off from my job and not being able to IM with someone I have taken a fancy to. ;-)

> > Some on the thyroid forum have been taking SAME for a long time with no poop out. (Note -one of them was on antiD's before and used SAMe to help wean off). Most also take calc/magnesium too.
>
> Well, that's encouraging. I hope the TMG doesn't poop out either then.
>
> > So perhaps the tyrosine and say 63mcg to 200mcg Selenomethionine form of selenium(Selenium 25mg to 75mg) together with the SAMe might work.
> > Let us know how you go.
>
> I do take selenomethionine...don't remember how long I've been doing so now, but recently I've tried to take at least 200 mg a day for dental amalgams leaking mercury. And I'm feeling good this week since the higher dose of TMG!

Just to let you know, I checked my multi and it has 50 mcg of "yeast-free L-Selenomethionine" per capsule. So I've been getting 100 mcg/day for a while, now going up to 150.


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