Posted by tropicalmanna on October 18, 2009, at 2:55:52
In reply to Memantine as a reversible MAO Inhibitor?, posted by Rosy Crucifiction on October 15, 2009, at 13:07:33
Thank you for the article!
In my experience high dose memantine works well as a fast acting antidepressant but is tricky to maintain because multiple high doses accumulate upon days to cause an unpleasant dissociative state. If anyone here is thinking about trying high dosing one must be aware that as a monotherapy it may make you experience OCD-like behavior and negative symptoms of schizophrenia. In addition, its 5HT antagonizing properties diminish the antidepressive response. Combined with a serotonin boosting med or a d2-antagonist one may be able to harness memantine's full potential for long-term use.
~TM
poster:tropicalmanna
thread:921016
URL: http://www.dr-bob.org/babble/20091012/msgs/921348.html