Posted by Medline on January 28, 2009, at 4:04:43
In reply to Re: @Vincent » Medline, posted by kingcolon on January 27, 2009, at 23:16:33
Very nice stack you have there. Great to hear you're doing well. ;-) I'm not sure the Lamotrigine is beneficial, maybe you should ask your Pdoc if you can taper it down? Or do you have moodswings, hypomania, Borderline disorder or something like that? Combining the NDRI Bupropion with low-interaction SSRIs like sertraline, citalopram or escitalopram is a great strategy I think. They offset each others side effects and the AD-effect is very robust, there are some studies out there proving that this combo is a good one. I used Modafinil and Bupropion (in combination with Escitalopram) but unluckily they cause too much anxiety for me. Low dose Buprenorphine is great for some people with treatment resistant depression from what I read. I tried it, but felt nothing (also "intoxicating doses"). Tramadol, Codeine, DHC do nothing for me too, I don't know why. ;-)
Maybe you should really think about kicking the Lamictal out when you have Pregabalin now.
I will modify my regimen soon and substitute Moclobemide with Escitalopram. It has more proven efficiency, is potent, fast-acting and has very low interaction potential. I don't think that the Norepinephrine the Moclobemide provides is very important for SA, I think it's more a Serotonin, Dopamine, GABA story (and probably Oxytocin, Endorphins...).
2 x Escitalopram 10mg
1 x low dose Selegiline 2.5-5mg twice per week
4 x Gamma-Butyro-Lactone 1.5ml
1 x low dose Cycloserine 50mg (taken for 2-4 months)At night:
1 x low dose Baclofen 25mg
1 x low dose Naltrexone 5mg (to avoid opioid receptor downgrade)On weekends: 2mg Clonazepam instead of GBL & Baclofen. Higher dose of Naltrexone (25mg on saturday) and 12.5mg on Sunday.
@Vincent:
I just read my last post again and it sounds a bit rude at daylight. Sorry! Have a great Birthday.
poster:Medline
thread:876329
URL: http://www.dr-bob.org/babble/20090104/msgs/876706.html