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Re: rasagiline superior to selegiline? » Jakeman

Posted by Donna Louise on May 31, 2006, at 21:05:43

In reply to rasagiline superior to selegiline?, posted by Jakeman on May 28, 2006, at 19:18:48

> I was wondering if anyone has tried rasagiline or has any comments about this article:
>
> Rasagiline : a neuroprotective smart drug?
> http://www.rasagiline.com
>
> I found this excerpt to be interesting:
>
> "The main therapeutic advantage of rasagiline over the other selective irreversible monoamine oxidase-B inhibitor selegiline (l-deprenyl, Eldepryl) is that rasagiline does not have the perhaps toxic amphetamine metabolic breakdown products of the structurally similar selegiline. Subjectively, rasagiline feels "cleaner".
>
> warm regards, Jake
>
>

But see, one of the main advantages of the transdermal delivery system is that you don't get the same amount of amphetamine metabolites, even if they were toxic which I have not read that they are. So this may be true if you are talking about oral selegiline but it is probably no 'cleaner' than EMSAM.

Donna


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