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Re: rasagiline superior to selegiline? Jakeman

Posted by yxibow on May 29, 2006, at 18:35:45

In reply to rasagiline superior to selegiline?, posted by Jakeman on May 28, 2006, at 19:18:48

> I was wondering if anyone has tried rasagiline or has any comments about this article:
>
> Rasagiline : a neuroprotective smart drug?
> http://www.rasagiline.com
>
> I found this excerpt to be interesting:
>
> "The main therapeutic advantage of rasagiline over the other selective irreversible monoamine oxidase-B inhibitor selegiline (l-deprenyl, Eldepryl) is that rasagiline does not have the perhaps toxic amphetamine metabolic breakdown products of the structurally similar selegiline. Subjectively, rasagiline feels "cleaner".
>
> warm regards, Jake


That was a biopyschiatry.com article copy -- they have some interesting information but one has to take the selections with a grain of salt. Nevertheless it has some interesting information.

It was recently approved for use in the US for parkinson's (www.azilect.com) and will be in pharmacies soon. It also has a tyramine restrictive diet and could theoretically cause dyskinesias though those are more common with levidopa administration

http://www.azilect.com/comingsoon/PrescribingInformation.pdf

 

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URL: http://www.dr-bob.org/babble/20060525/msgs/650197.html