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Re: rasagiline superior to selegiline? Jakeman

Posted by Larry Hoover on May 28, 2006, at 21:45:30

In reply to rasagiline superior to selegiline?, posted by Jakeman on May 28, 2006, at 19:18:48

> I was wondering if anyone has tried rasagiline or has any comments about this article:
> Rasagiline : a neuroprotective smart drug?
> I found this excerpt to be interesting:
> "The main therapeutic advantage of rasagiline over the other selective irreversible monoamine oxidase-B inhibitor selegiline (l-deprenyl, Eldepryl) is that rasagiline does not have the perhaps toxic amphetamine metabolic breakdown products of the structurally similar selegiline. Subjectively, rasagiline feels "cleaner".
> warm regards, Jake

I haven't tried rasagiline. Glad to hear it has a cleaner feel. I do not attribute toxicity to selegeline, though. No perhaps about it. Barring idiosyncratic toxicity, I mean. I do not attribute a general toxic effect to selegeline, period.





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