Posted by linkadge on April 21, 2006, at 17:37:50
In reply to Re: interesting- re clonazepam and 5-HT transporte, posted by SLS on April 21, 2006, at 16:05:46
Yeah, I suppose that agents like buspar and gepirone exert their anxiolitic effects via post synaptic 5-ht1a receptors.
I think that activation of post synaptic 5-ht1a receptors causes declaritive memory problems by inhibiting cholinergic function. 5-ht1a agonists are also called serenics. 5-ht1a receptor agonists are known to reduce REM sleep, and I think that is related to their supressing effects on cholinergic function.
OTOH, serotonergic agents are neurotrophic via post synaptic 5-ht1a receptors.
So I think that when you take a 5-ht1a agonist, it kinda calms you down, shuts you up, and gets you growing new brain cells instead of blabbing about the connections you've already made.
Linkadge
poster:linkadge
thread:629584
URL: http://www.dr-bob.org/babble/20060417/msgs/635621.html