Posted by linkadge on April 20, 2006, at 20:52:10
In reply to Re: Drugs versus Psychotherapy - Backlash? » linkadge, posted by zeugma on April 20, 2006, at 19:27:58
Interesting. Another thing to consider is that all of the currently available SSRI's increase the synthesis of a very potent gabergic neurosteriod called allopregnanalone. I believe that it is an intrinsic effect of the molecule, and not an effect of an SSRI in general.
This could definately confound some of the responces. Ie a person could respond to this
mechanism but perhaps still have a s/s transporter gene.SSRI's often made my anxiety much much worse. They also had minimal effect on my depression.
They helped my depression a little when things weren't stresfull, but heavy stress + SSRI's always made me near psychotic.Heres what I never understood. They don't discover these drugs by doing all of these advanced biochemical studies in humans. They discover all of the antidepressants by throwing regular mice in a vat of water and seeing which ones keep the mice swimming longer. They don't base their presumptions on the ability of the drugs to fix any rat's bad biochemisty, so why all of a sudden are these drugs supposedly fixing humans at the biochemical level? Oh sure, some of these drugs can keep you "swimming" a little longer, but they're a far cry from feeling good.
Linkadge
poster:linkadge
thread:629584
URL: http://www.dr-bob.org/babble/20060417/msgs/635391.html