Posted by zeugma on April 23, 2006, at 18:34:05
In reply to Re: interesting- re clonazepam and 5-HT transporter » zeugma, posted by jedi on April 23, 2006, at 0:00:47
Hi,
10mg/kg would be like a 220lb person taking 1000mg daily of clonazepam for 10 days. Unless I'm reading this wrong, sounds like enough benzo to knock off a horse, much less a rat. How can anything be inferred from such high dosages.
>>hi
I don't think the dose equivalences across species works like that. The rat's metabolism, CNS, etc., are different enough from ours to make it an interesting question indeed whether anything can be inferred from such dosages :-)
-z
poster:zeugma
thread:629584
URL: http://www.dr-bob.org/babble/20060423/msgs/636299.html