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Re: hand holding » Lorraine

Posted by Elizabeth on July 16, 2001, at 21:20:07

In reply to Re: hand holding » Elizabeth, posted by Lorraine on July 15, 2001, at 21:11:31

> > > >What's your understanding of the mechanism of action? (By "active ingredients" I really meant the chemical(s), not the name of the plant, BTW.) I looked it up in a few places; it sounds interesting.
>
> I was afraid you'd ask that and, of course, I haven't a clue.

Of course I'd ask it! Seriously, I'm planning on looking it up myself at some point (it's right at the bottom of my things-to-do list < g >).

> GABA might help also.

I have trouble believing that oral GABA would ever make it into the CNS.

> > > > Although I don't generally have skin-picking problems, I developed one (temporary, thankfully) when I tried adding Cylert to Nardil (MAOIs can be expected to potentiate psychomotor stimulants).
>
> Good to know. So you tried Nardil with a stimulant? And, I take it has edgy results?

Several stimulants, not just Cylert. Some people can tolerate it, some can't. The main risk is hypertension, of course.

> Isn't temperature intolerance tied to thyroid function?

Theoretically. But I've had a lot of thyroid tests and they've always been fine.

> Also, I read somewhere about excess dopamine causing this.

I have a feeling that's not a problem I have. < g >

> Yeah, it really sucks, but I think you have hit it right on the nose here. Serzone put me to sleep--even with Wellbutrin in the am. I hated it. Remeron and Nardil remain to be tried.

FWIW, I didn't get tired on either of those. (Then again, I'm hard to sedate, as I mentioned.)

> So, this is the other piece of bad news. I know--just seems impossible so that probably means back to an all-purpose AD of some sort and your hunch about an MAO may be right.

I don't understand -- what was the bad news?

> I had a pretty bad reaction to Inderal. I think it worsened my depression, which Jenson says it's prone to do--actually he says that people who take it have a five-fold increase in their AD dosage.

That's interesting. What I've read has suggested that the "beta blockers cause depression" thing has been greatly exaggerated (because people with cardiac disease are at increased risk of depression to start with).

> Anyway, bad luck for me. But he also mentions long lasting Betaxolol and I'm wondering if that might be your long lasting Beta-blocker.

Betaxolol is a good one. It's considered safer if it's necessary for a person with asthma to take a beta-blocker. It's beta1-selective, as your doctor says (so is atenolol, which I found didn't work for panic).

> Well, that's funny because I think I thought I'd jump out of my skin on them.

On opioids? Why?

> Hypersomnia. Well, I'd say unmedicated I sleep a lot, always have and it got worse with depression. Leaden paralysis--that pretty much describes it to a tee.

Leaden paralysis is specifically supposed to mean a feeling of heaviness in the arms and legs.

> OK--I'm moving toward MAOs I think. Thanks for really sticking with me on this. It helps immeasurably.

Well, sure thing. It's nice to talk to you.

> > [re side effect sensitivity]
> > > Ain't that a b****. I suspect your right though. Still wish I hadn't opened that particular pandora's box.
> >
> > > > Huh. In what sense is it a Pandora's box?
>
> You can't close it.

Wait -- what was "it" again? < g >

> Dudette to you < vbg >

Your Dudeliness.

-elizabeth


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Psycho-Babble Medication | Framed

poster:Elizabeth thread:67742
URL: http://www.dr-bob.org/babble/20010714/msgs/70398.html