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Re: Amisulpride and Selegiline

Posted by AndrewB on May 30, 2000, at 1:57:39

In reply to Re: Amisulpride and Selegiline, posted by michael on May 29, 2000, at 16:38:08

> How about selegiline 10mg/day and low dose amisulpride?
>
> I think both work to increase dopamine levels, although via different mechanisms?
>
> Theoretically, would therefore potentiate/reinforce each other?
>
> Any thoughts - or corrections, etc?

Michael,

I've thought about combining selegiline and amisulpride. They could potentiate one another. I remember someone saying that they had combined selegiline (low dose) with amineptine, another dopaminergic. It seems though from the posts I've read and other personal reports that selegiline has little or no noticeable psychological effect on people at low doses. With this is mind, I wonder just how effective a potentiator of amisulpride it might be. I am going to try entacapone, a COMT inhibitor that acts to increase dopamine at the synapse, as an augumentator to amisulpride. Hydergine, a smart drug, is also dopaminergic and another possible augmenting agent for those with mental slowness.

Michael, what have you decided on the adrafinil. Is it working for you? I might try it as my reboxetine pooped out.


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