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Re: olanzapine vs. amitriptyline » Brainbeard

Posted by Bob on May 25, 2010, at 11:41:05

In reply to Re: olanzapine vs. amitriptyline, posted by Brainbeard on May 25, 2010, at 7:33:56

> > Which would you rather take if they were hypothetically of roughly equal therapeutic value? I understand that olanzapine has those pesky weight gain and diabetes problems, but the amitriptyline has weight gain too, and those super-pesky anti-cholinergic effects.
>
> I have 'till now shunned olanzapine, even though I have been frantically searching for a 5HT2A/C-antagonist that doesn't increase prolactin. But indeed, it being diabetogenic plus likely to induce weight gain have kept me off.
>
> I have been using low dose amitriptyline since many months now. I like the drug. I have been able to avoid weight gain so far.
>
> A friend of mine has very good results with olanzapine. He takes it IN THE MORNING - and it stimulates him!! Can you believe that?
>
>

That is hard to believe. He must be on a small dose. I would think higher doses would be soporific.

I tried amitriptyline and within 2 days the brain fog, constipation and fatigue were becoming quite troublesome. Then I began to get irritable and more depressed. I'm guessing that for you this drug is pretty tolerable?

Bob

 

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