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Re: olanzapine vs. amitriptyline

Posted by Brainbeard on May 25, 2010, at 7:33:56

In reply to Re: olanzapine vs. amitriptyline » linkadge, posted by Bob on May 21, 2010, at 20:03:53

> Which would you rather take if they were hypothetically of roughly equal therapeutic value? I understand that olanzapine has those pesky weight gain and diabetes problems, but the amitriptyline has weight gain too, and those super-pesky anti-cholinergic effects.

I have 'till now shunned olanzapine, even though I have been frantically searching for a 5HT2A/C-antagonist that doesn't increase prolactin. But indeed, it being diabetogenic plus likely to induce weight gain have kept me off.

I have been using low dose amitriptyline since many months now. I like the drug. I have been able to avoid weight gain so far.

A friend of mine has very good results with olanzapine. He takes it IN THE MORNING - and it stimulates him!! Can you believe that?


Current meds: 10mg melitracene + 0.5mg flupentixol; sertraline 100mg; amitriptyline 25mg; gabapentin (Neurontin) 300mg; melatonin 0.3mg. PRN: diazepam (Valium) 2.5-5mg.


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poster:Brainbeard thread:948075
URL: http://www.dr-bob.org/babble/neuro/20100223/msgs/948758.html