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Re: fish oil , NO, EPO » tealady

Posted by Larry Hoover on April 25, 2005, at 11:08:21

In reply to Re: fish oil , NO, EPO » Larry Hoover, posted by tealady on April 10, 2005, at 18:04:52

> I've been seeing this fish oil promotion of NO in many differing places..just forget where
> here's another
> http://www.oilofpisces.com/cholesterol.html
>
> "Promotion of nitric oxide induced endothelial relaxation "
> perhaps its just a side effect of the macrophages producing increased NO while phagocyting along the endothelial linings of the blood vessels ?
>
> Just thought that maybe if someone had too much NO already, increased amounts might up the oxidation and peroxynitrates (OK I don't fully understand this) damage too much causes, basically just fishing for a reason why some of us may feel worse of fish oil....maybe those of us who tend to have maybe a fair amount of inflammatory stuff going on..as in autommune disease etc. Just thinking along those lines
>
> Jan

It's free unregulated NO that's a problem. As a pressor-modulator (a controller of blood pressure/flow), NO is a good guy. If free NO is a problem, then you need to deal with peroxynitrite stress, as per Dr. Martin Pall.

http://molecular.biosciences.wsu.edu/faculty/pall.html

How are you doing, Jan? You're kind of scarce these days.

Lar

 

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