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Re: L-glutamine ..forgot to add,,,JLx..

Posted by mmb on October 17, 2004, at 7:03:07

In reply to Re: L-glutamine ..forgot to add,,,JLx.. mmb, posted by tealady on October 17, 2004, at 5:51:24

> Just trying to give some reasons why you find it beneficial..like you have good levels of estrogen, progesterone, enough cortisol (high is fine here although I realise too high for too long is no good), and get enough exercise..so it works for you. I know you did'nt need to know it works for you, just thought I'd give some reasons as to why it might work for you and not for others.
>
> Glutamine syntase is an enzyme needed to break down the glutamate..to have enough of it you it looks like (from those studies)you need good levels of cortisol, T3..and you've got enough.
>
> Estrogen, progesterone, I think can alter the pathways.
>
> One word of caution though for anyone considering or even likely to get pregnant..Dr Mercola's article that JLx linked to pointed out glutamine is probably dangerous to the foetus, as is gingko
>
> Best, Jan
>
>
Thanks Jan,
to be honest I have no idea how it works. In one of the above articles it says "To produce enough GABA, people need an abundant supply of the amino acid glutamine - glutamine is the nutritional precursor of GABA which has an antianxiety effect. [Acta Paediatr Jpn Oversea Ed (Tokyo) 20(1978): pp.11-23] In another study, people taking glutamine showed significant reductions in their feelings of anger and fatigue. [Rogers, et. al., Effects of Glutamine on IQ, Tex. Rep. Biol. Med. 5]". My guess is that glutamine crosses blood barrier and converts to GABA (at elast some of it). What I found out is the same as many studies confirm. More L-glutamine does not make things better. After noticing benefits I tried to increase L-glutamine to 1,5-2 g each night but the effect was the same so I came back to 1g (morning and evening). So, I am sure that these small amounts make significant difference in anxiety reduction (that is my experience). Also, I noticed benefits in social anxiety reduction (like meeting people, looking them in the eyes etc). Before I did that with great deal of effort, but now it is not problem. It may be as well beneficial to ADHD, as some studies support this theory.
But, as with any supplement it may not work with everybody. For example, I have bad experience with GABA while some people on Google groups swear by it. We are all different.

regards,
mmb


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