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Re: Confused about methylation...Larry H., DSCH, help? » Larry Hoover

Posted by DSCH on November 10, 2003, at 12:40:29

In reply to Re: Confused about methylation...Larry H., DSCH, help? » JLx, posted by Larry Hoover on November 10, 2003, at 9:11:12

Good post, Lar. Seeing as you're the one with formal education on biochemistry, I don't have anything to add, other than ask why methylcobalamin is bad if it appears necessary for the methionine synthase reaction. Only the 'used-up' form of methylcobalamin consumes SAMe (but at what ratio does the synthase reaction require the methylcobalamin? If it is less than 1:1 you come out ahead on SAMe it seems to me).

Also, I find DMAE's being on the contraindication list for under-methylated persons curious. Sahelain classifies it as a methyl-donor.

I will again state that in my experience, the most dramatic thing that kicked TMG "on" was taking supplementary magnesium.


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