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More....poor man's SAMe? » JLx

Posted by JLx on November 10, 2003, at 7:01:39

In reply to Confused about methylation...Larry H., DSCH, help?, posted by JLx on November 10, 2003, at 6:49:03

Again from Dr. Walsh, on Alternative Mental Health, (this is from a discussion with other doctors apparently),

"A quick way to test for need for methylation therapy is to carry out a cautious trial of SAMe. Within a week or two you should have your answer. If she clearly is improving on the SAMs (which is frightfully expensive)..... you can get usually the same benefits (albeit more slowly) using methionine plus calcium, magnesium, and B-6. This should be side-effect free unless (a) the methylation is begun too abruptly or (b) the patient has a rare genetic enzyme disorder which disrupts the SAM cycle. We've found that direct methylation is usually more successful than tinkering with the SAM cycle. The primary way humans receive most of their methyl groups is from dietary methionine. It's often hard to improve on Mother Nature. (Jan 20, 2003)'

So, "methionine, calcium, magnesium and B6" is SAMe equivalent?

How much of each would be likely?

When I've tried SAMe not only was I less depressed but I had more energy too.

I've been "trial and error" with tyrosine for about 6 weeks now and it's going pretty well. But when I first tried it, I also was using up some SAMe I already had, about 18 days worth. I really noticed when I ran out...less good mood, and considerably less energy.

I've taken methionine (500 mg) now for a few days and think it has some slight bit of the same impact. I've also added TMG, about 400 mg per day for about 5 days.

I already take magnesium and B6 with all my aminos, but don't take calcium as a rule except in tiny amounts as it makes me crazy. ;)


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