Posted by tensor on January 22, 2013, at 6:47:25
In reply to Re: hyperfocus' response » tensor, posted by SLS on January 22, 2013, at 3:27:58
> > I have had so many depressive episodes in my life and a sustained remission is not likely.
>
> That might appear true inductively, but perhaps not deductively. A long history of treatment failures sets an empirical trend, but not an absolute certainty. I don't think you can conclude deductively that a sustained remission is unlikely until you have exhausted all treatment possibilities. While I haven't reached full remission yet, my robust response to my current treatment regime has been a surprise to me; this, after 30 years of treatment failures. I cannot say with certainty that you are likely to respond to prazosin or minocycline, but it is certain that you cannot pronounce yourself untreatable until you do.No but it's good to know they exist as a viable option, I have learned alot from you Scott.
I agree, the number of combinations with meds, especially when we tend to borrow more meds from other fields, is huge. However, for every cycle of depressive episode and remission, it seems to be harder and harder to get the brain going again. What started as a depression easily treated with a medium dose mirtazapine has over the years evolved into something different.
I can't remember when I took less than four meds. I do remain hopeful and I try to remedy the situation with more than medication, although I really would like to see more meds emerge, labeled as 'next generation'.>I find sighted hope to be more compelling than blind hope, so I educated myself in order to find it.
This is the best I have read in a while :-) I hope you don't mind if I use it.
> An interesting mix might include Lamictal, Abilify, minocycline, and Wellbutrin. This treatment proposition is not necessarily designed with you in mind. I don't recall your symptoms or treatment history. However, it is an example of a new way of using old drugs. Polypharmacy may be necessary in your case until new treatments emerge from medical science.That is an interesting combination. Looks dopaminergic. I tried alprazolam recently but didn't like it at all. I have had some problem with anxiety but today is a better day and I'm back to clonazepam. I decided to give Concerta another shot so I took 36mg this morning. Didn't feel anything positive a.m. but the afternoon has been good. Been out in the sun and actually ran for awhile.
I also take 300mg Seroquel and 200mg Lamictal. I used to like modafinil alot but I have complained for a long time that its efficacy has declined. I read that NE-alpha1 antagonists may block the actions of modafinil. Hmm.. like Seroquel and many more.> You are a hard worker, and you deserve to win.
So do you, Scott, and all sufferers out there.
/tensor
poster:tensor
thread:1035749
URL: http://www.dr-bob.org/babble/20130112/msgs/1036065.html