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Re: Agomelatine and Tranylcypromine for OCD

Posted by sigismund on March 13, 2011, at 13:15:22

In reply to Agomelatine and Tranylcypromine for OCD, posted by Dr. Fischer-Terworth on March 13, 2011, at 5:50:35

>At the beginning I thought it also helps with
OCD, as 5-HT2c receptor antagonism is also a
feature of some SSRI like Fluoxetine.
But, however, over the months I think that OCD has worsened (YBOCS:15).

>Can it be that the 5-HT2c antagonism is not good
for OCD as negatively affecting serotonergic
transmission?

I am not clear about OCD, but I think you are right. That would be my guess too.

 

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poster:sigismund thread:980414
URL: http://www.dr-bob.org/babble/20110220/msgs/980432.html