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Re: SSRI Induced HPTA Disruption

Posted by SLS on February 6, 2009, at 20:11:14

In reply to Re: SSRI Induced HPTA Disruption, posted by bulldog2 on February 6, 2009, at 19:34:39

> Here's a link on buspar
> The book is Beyond Prozac by Michael Norden
> He claims
> 1. buspar augnments ad effect of prozac.
> 2. lessons side effect of prozac
> 3. lessons sexual sides in 70% of prozac uses
> Probably due to partial agonist effect...see wikipedia that blocks certain serotonin receptors that cause anxiety and sexual sides

One thing often overlooked with buspirone is that its metabolite, 1PP, is a potent NE alpha-2 antagonist - just like Remeron. I can't imagine that this wouldn't add to the augmenting utility of this drug.

Thanks for the link, by the way.

- Scott




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