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Re: SSRI Induced HPTA Disruption

Posted by bulldog2 on February 6, 2009, at 19:34:39

In reply to Re: SSRI Induced HPTA Disruption » bulldog2, posted by SLS on February 6, 2009, at 18:28:39

> > I remember reading a book about ssris. Don't recall the title. The doc said that Wellbutrin doesn't do a good job reversing sexual problems.
> >
> > Now the good thing is that he used buspar in conjunction with ssris and that in most cases restored sexual function. I believe that buspar acts as a block on one of the serotonin sites that causes the problem. Maybe I can find the book. But for him buspar and an ssri was the magic combo.
>
> I'd love to know which receptor that is. Is the combo good for the depressive disorder itself? Does Buspar make the antidepressant work better?
>
>
> - Scott

Here's a link on buspar

http://en.wikipedia.org/wiki/Buspirone

The book is Beyond Prozac by Michael Norden

He claims

1. buspar augnments ad effect of prozac.
2. lessons side effect of prozac
3. lessons sexual sides in 70% of prozac uses

Probably due to partial agonist effect...see wikipedia that blocks certain serotonin receptors that cause anxiety and sexual sides

 

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