Posted by CaptainAmerica1967 on December 18, 2008, at 19:30:21
In reply to Re: TRD --SLS, CPTAmerica » CaptainAmerica1967, posted by desolationrower on December 18, 2008, at 12:26:42
Wow, interesting...learn something new everyday.
I'm familiar with vertigo and Meniere's Disease, but had never heard of Betahistine. I guess it's not available in the USA, but available mainly in the UK and maybe Canada.
I have to read over the information again, but it sounds like a good med to try. Doesn't specify if there's any drug interaction with an MAOI, but I'll search for some more information on it.
Wikipedia states that "The H3 receptor has also been shown to presynaptically inhibit the release of a number of other neurotransmitters (i.e. it acts as an inhibitory heteroreceptor) including, but probably not limited to dopamine, GABA, acetylcholine, noradrenaline, and serotonin" so betahistine as an H3 receptor antagonist would increase these neurotransmitters.
Thanks for the info...interesting to see that a study is being done on betahistine in relation to atypical depression.