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Re: provigil discussion

Posted by mike99 on February 25, 2006, at 13:13:45

In reply to provigil discussion, posted by tessellated on February 25, 2006, at 12:31:34


That's interesting. Thanks for the info Tessellated.

Remeron, Tenex and Clonidine work on presynaptic autoreceptors (by central alpha-2 antagonism and agonism).

I wonder how significant the increase in peripheral NE is, as I think this would/should be clearly stated in the drug monograph.

I can't take stims due to extremely excessive cardiovascular activation and so I wonder if I'd have the same problem w/ Provigil if it in effect increases NE.

Any thoughts on this would be appreciated.

Thanks again for the feedback.

And yeah, I agree the patenting of the active isomer strategy has gotten a little out of control, though I imagine it's sometimes beneficial.



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poster:mike99 thread:612884
URL: http://www.dr-bob.org/babble/20060219/msgs/613113.html