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Re: buprenorphine WEEK 7 » ed_uk

Posted by pseudoname on January 4, 2006, at 10:26:03

In reply to Re: buprenorphine WEEK 7 » pseudoname, posted by ed_uk on January 3, 2006, at 15:03:01

> > I first got benefit in my second week, when I titrated up to 1.8 mg.
> It's interesting that the benefit was quite delayed.

I guess I worded that poorly. Starting with 0.1 mg on the first day, it took me about ten days, increasing the dose gradually due to side effects, to get to 1.8 mg. But on the very first day that I took a 1.8 mg dose, I got the benefit in about two hours.

It took Elizabeth 3 days to get the benefit, but I'm not sure how long it took her to titrate up to her therapeutic dose-level.

> Is it bitter?

It is bitter — bitter!

> > When I've gone WITHOUT bupe for a day, however, I've had really strange memory lapses.
> Interesting. Makes me think of state-dependent memory.

Well, I never had any recovery of the memory on bupe or off, so I don't think we can call it state-dependent. Just forgotten! :-)

Hmmm. But that is not a bad thing to keep in mind if I have to study for any tests: make sure my buprenorphine level is the same when studying as when taking the test.

> It's interesting that bupe seems to be increasing your motivation.

(Chuckle.) I don't want to overstate that! I'm still pretty lazy, but... humm.... yes, actually I guess my motivation is increasing! I was experiencing it more as feeling like I *had* to do stuff now, but that surely is "motivation", even if it feels burdensome.

What would I do without Babblers to help me think these things through?

> Opiophobes often talk of people becoming apathetic on opioids.

Somebody posted that she reacts to tramadol (Ultram®) like it's an amphetamine. It makes her run around cleaning her house and so on. I haven't had that experience yet.




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