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Re: opioid motivation

Posted by reefer on January 5, 2006, at 13:17:54

In reply to opioid motivation Declan, posted by pseudoname on January 5, 2006, at 9:32:39

> I'm going to experiment with increasing my buprenorphine dose slightly (like from 3 mg/day to 4.5) to see if the "motivation" angle might improve more.
For me taking 8 mg s.c inj. makes no difference at all compared to taking 4 mg s.c inj. I would very much like to try going much much higher. Like between 16 and 32 mg i just can't afford to waste my expensive hard to obtain Subutex. There is something that seems to work VERY much better than upping the dose. And that is spreading the dose as much as possible. Taking 4 mg in the morning will make me fine for 3 - 4 hours, just like 1 mg will. But taking 1 mg every 4 hours is a whole other story. This will make me feel fine pretty much all day long. So same total dose spread out is a whole other story than all at once. And this makes me think i really would like to get the patches instead. Since they release a low, stable and constant dose during the entire time it is working: between 72 hours and 7 days depending on the patch if i understand this correctly. I'm not sure if the patches deliver enough though. I think the 40 mg 72 hour patches delivered 70ug per hour. That is 280ug parenteral bupe during 4 hours. Should equal around 400ug SL. And the dose i like best is 0.5 mg every 4 hours. So this might very well be near perfect. There is also the possibility to add another patch if a higher dose would be needed.

Anyway until i can get my hands on patches i will try and make a nose spray which i will administer every hour. I will report on how that works.




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