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Tricyclics and anhedonia

Posted by Squiggles on November 6, 2005, at 9:19:44

Before taking lithium, I did take imipramine,
which felt like taking an organophosphate; not only did it not treat my depression, but i broke
out in a rash and almost fell into the subway
tracks from dizziness and disorientation. I
slept about 3 hrs. per night. Not for me-- but obviously for others.

In comparison to lithium which (with the exception
of dose-related brain mishaps) imipramine really
feels like you're taking a pesticide, imho, does not compare to the excellent clarity of the cognitive state that lithium provides, and does not eliminate "anhedonia".

In my observation of a particular case in mind,
"anhedonia" hangs over one's head like the fog of a bad S-U-V day in L.A., every day. Perhaps that is the case with many tricyclics. But imipramine is strong enough to eliminate clinical depression where others, esp. SSRIs are not, and so is the only option in this case;


- are there alternatives/adjuncts equally strong
to imipramine for clinical depression which
also target "anhedonia"?

- would opiates work for clinical depression,and if so are there any legal ones or simulated ones available?

Thanks for reading.





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