Posted by Squiggles on November 6, 2005, at 12:39:36
In reply to effexor is supposed to have opiod effects..., posted by iforgotmypassword on November 6, 2005, at 11:32:44
> there is an abstract on pubmed about this, i also recall mention of it having a similar structure to tramadol (Ultram). this may make sense as it is supposed to be a phenethylamine, and that is supposed to carry with it opiod properties. (that seems to be why D-phenylalanine is used for chronic pain)
I don't know the chemistry of pain killers,
but I know they can be as addicting as
opioids, e.g. OXYCONTIN, so perhaps they
habituate the same areas or parts of the brain.
And Ultram, as pain killer may fall into this
category?Anyway, there are some issues that should
be kept distinct in this opiate question,
i think:a) is the chemistry of opiates superiour
to that of other ADs for depression;b) can the addicting properties be managed
well so that it can be taken for a long time?c) if the above are feasable, is there a
political/government/economic quagmire
that cannot be resolved *even if the opiates
prove to be better*?d) can substitutes like the one you mention
(Effexor was too weak in this case of endogenous,
maybe even organic depression) be made chemically
equivalent.thanks for your input.
Squiggles
poster:Squiggles
thread:575925
URL: http://www.dr-bob.org/babble/20051106/msgs/576002.html