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Dry mouth.... Stablon (tianeptine) side-effect?

Posted by sukarno on June 24, 2005, at 5:16:10

In reply to Developing side effects to tianeptine (Stablon), posted by sukarno on March 25, 2005, at 5:30:58

I'm curious if anyone else here has taken Stablon (tianeptine, an atypical tricyclic antidepressant...supposedly with no anticholinergic action).

Have you ever felt thirsty on it? I never have until recently. I had raised the dose from 25mg to 37.5mg (2 to 3 tablets respectively) and noticed some thirst, sometimes intense. I now drink double (3 litres) the amount of water than I used to.

Is this something I should be concerned about? I thought Stablon doesn't have anticholinergic or antihistaminic effects.

Ed, are you still around? You know a lot about psychopharmacology. :)

I also have been steadily raising my Pepcid (famotidine) dose to quite a high level. I'm on 20mg 6 to 8 times a day since I'm developing a tolerance to it and the acid was coming back (I have GERD).

I'm not sure which drug is responsible...or maybe both are.

Can Pepcid, since it is an H2 receptor antagonist become *nonselective* and target H1 histamine receptors too?

Thanks in advance! I drink a lot of water but it doesn't seem to help, but if I lower the Pepcid, the acid will come back with a vengeance and if I cut the Stablon down I'll get some headaches as a withdrawal reaction.

Thanks again. :)

Paul


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poster:sukarno thread:474445
URL: http://www.dr-bob.org/babble/20050622/msgs/517891.html