Posted by not_so_pro_social on April 24, 2005, at 2:41:13
In reply to Re: Klonopin versus all other benzo's, posted by Paulbwell on April 24, 2005, at 2:30:36
> > > .5mgs Klo=10mgs of Diazapam, in other words it has 20x the Gaba binding capacity of Diazepam.
> >
> > Even if it was true (20x more - where did you read it???) it means nothing. .5mg Klonopin=10 mgs Diazepam have pretty much the equivalent mode of action.
>
> I have read this on MANY Benzo equivelency tables,I was talking about the part about higher GABA binding, not mg per mg dosage.
The thing that Klonopin is only 0,5 and Diazepam 20 (this would be actually 40x in your calculations) doesnt necessarily mean that binbing to GABA receptors is 20 or 40x more. Just that Diazepam has higher mg per dose and thats all. Nothing else. If you disagree please post some Pubmed studies or something.
poster:not_so_pro_social
thread:487639
URL: http://www.dr-bob.org/babble/20050423/msgs/488674.html