Psycho-Babble Medication | about biological treatments | Framed
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Re: PS: Sam-e; causes 5-HT, NE, DA depletion?

Posted by jemma on April 29, 2003, at 11:59:13

In reply to Re: PS: Sam-e; causes 5-HT, NE, DA depletion?, posted by stjames on April 28, 2003, at 22:22:03

I'm confused, here. Okay, I admit that one can't draw conclusions from massive doses injected into brains of rats. What concerns me more is the statement that methylation increases with age, and that SAMe is a "limiting factor" in methylation. I had thought that methylation was a good thing, but apparently it's associated with Parkinson's, dopamine depletion, and all round deterioration of the brain. So if SAMe levels decline with age, perhaps it's the brain's effort to counteract these negative effects? And by boosting SAMe, we're only increasing the toxic levels of methylation? I know it feels good in the short term, but alas so do so many things that are bad for us. As I said, I'm confused.

None of this, however, is likely to stop me supplementing with betaine, folic acid, B-6, and B-12. Which brings me to my next question. Larry, I know you're also based in Ontario. Have you found a good source for betaine-TMG? I'm finding it hard to locate in the health food stores. They only seem to have betaine-HCL.

- jemma




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