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Re: Judy -- Selegiline, Pindolol, Melatonin & Estrogen

Posted by Scott L. Schofield on January 2, 2000, at 14:15:56

In reply to Re: Judy -- Selegiline, Pindolol, Melatonin & Estrogen, posted by anita on January 1, 2000, at 16:50:38

> Hi Judy,
> I've always had low estrogen and have suspected it may be a factor in depression. All I've read about estrogen seems to indicate that this could be the case. However, when I was on nardil, the only AD that actually seemed to have a significant effect, my estrogen levels got a little lower and my testosterone level was sky-high.
> I'm only in my early 30s, so I think for me I've just had low estrogen all my life (late puberty, painful and irregular and usu. 30+ day periods). I think I felt better when I was taking birth control pills years ago, but then again that was a better time of my life.
> Anybody know of any studies on estrogen and the sleep cycle?

Just a quick contributionÖ

The use of estrogen for treatment-resistant depression in women is another one of those hormonal treatment strategies that are sometimes employed, regardless of baseline levels. As another point of interest is the fact that many clinically depressed women - even those who are treatment-resistant - feel better while they are pregnant. Afterwards, depression usually returns. I imagine that this phenomenon is directly related to the changes in estrogen and progesterone levels, but I don't recall the sequence of these changes and how they may correlate to the observed changes in mood. The football game is on and I'm too lazy to look into it right now.

I donít know anything about a relationship between estrogen levels and sleep. The effect that Nardil had on your testosterone levels is interesting. I donít know anything about that either. Sorry.

- Scott




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