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Re: Judy -- Selegiline, Pindolol, Melatonin & Estrogen

Posted by Judy on December 26, 1999, at 10:59:00

In reply to Judy -- Selegiline, Pindolol, Melatonin & Estrogen, posted by Zeke on December 25, 1999, at 23:53:27

Thanks, Zeke! I will do a medline search on estrogen. I have a 'gut' feeling that estrogen, or lessening amounts of it, may be playing a significant part in the changing personna of my depression and the reason why previously used AD's affect me differently now. (Or perhaps my aging synapses and receptors are just rolling over and dying at a faster rate!)

Melatonin? Is that indicated with MAOI's? Not sure if anyone knows what is/isn't indicated with Selegiline at high doses. Another medline search maybe. Besides the sleep problems, I DO need Xanax (or something) for the anxiety that Selegiline isn't touching - or may even be exascerbating.

Great explanation of Pindolol's mechanism. I too wondered why it would be of benefit with Selegiline. In general, I've always wondered why it is that SSRI's just DO NOT work for me. They make me so fatigued that I wouldn't notice any benefit if it were there. Is it possible that Seratonin just isn't my problem brain chemical, or is there another mechanism of SSRI's that pushes my 'coma' button? Is it possible that Pindolol might lessen my SSRI- induced fatigue?

I'll do those web searches when I have a quiet moment today. If I find anything promising (or confusing), I hope you'll be here to run them by. Thanks again. Judy



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poster:Judy thread:17103
URL: http://www.dr-bob.org/babble/19991212/msgs/17514.html