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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 12 of 12. This is the beginning of the thread.
Posted by sabre on December 16, 2004, at 16:58:57
I tried B6 for the first time yesterday - 240mg.
I also took tryptophan (and Mg) - about 1/3 tsp in the evening. I have tried it a few times and every time I suffered headaches and nausea the next morning. However I had no negative reaction this time. Felt quite good.
It makes me wonder if the reason Lexapro, Moclobemide etc caused problems was due to deficiencies in B6 and Mg?
sabre
Posted by TeeJay on December 16, 2004, at 20:09:03
In reply to Tryptophan and B6, posted by sabre on December 16, 2004, at 16:58:57
Hiya sabre,
Dunno what others will think, but I reckon thats a pretty heavy dose of B6 to be taking. Ok I guess if its on an occasional basis, but I wouldnt want to be taking more than 100mg max for any length of time (and some consider that to be a bit heavy too).
Just my thoughts anyway
TJ
Posted by sabre on December 18, 2004, at 0:55:09
In reply to Re: Tryptophan and B6, posted by TeeJay on December 16, 2004, at 20:09:03
Hello TJ
Thanks for that advice. I was looking at a book called ''Brain Candy'' and they also mentioned there were problems with taking high doses of B6. They said don't go over 100g per day because high doses over time can cause neurotoxicity. Is that your concern too?Soon after sending my post I began to develop a headache and nausea. I had to brave the shopping mall and felt quite weird, anxious and nervy.
The wall to wall people, babies crying, music were almost unbearable. It was as though the volume and intensity had been jacked up. The headache and that SSRI 'rats gnawing your gut' sensation made it a great Christmassy experience. I did the bare minimum and went home and crawled under the doona.I also had difficulty getting to sleep after taking the Tryptophan the previous night but put it down to work worry but now I think it was the T.
I think Tryptophan has done its last dash with me. I don't know whether it is like an SSRI where you have to take it for weeks until you start to tolerate it?
Anyway as I was crawling through the tinsel and din at the shopping centre I managed to detour into a health food store and bought a bottle of B3.
I'll ditch the Tryptophan but continue experimenting with a lower dose of B6 and try the B3.So far only tyrosine and magnesium have done anything....
sabre
Posted by tealady on December 18, 2004, at 3:10:24
In reply to Re: Tryptophan and B6, posted by sabre on December 18, 2004, at 0:55:09
> Hello TJ
> Thanks for that advice. I was looking at a book called ''Brain Candy'' and they also mentioned there were problems with taking high doses of B6. They said don't go over 100g per day because high doses over time can cause neurotoxicity. Is that your concern too?
>I think it does cause neuropathy in high doses..
so B6 is something you Don't want to take over a long period in a high dose.On way it works is by supporting tyrosine hydroxylase..which (I think) gets depleted by SSRI's, could be wrong as I've a dreadful memory:) but one of those enzymes we need a lot of
, anyway the mag, B6 and tyrosine are a good combo for this reason.
> So far only tyrosine and magnesium have done anything....http://www.dr-bob.org/babble/alter/20041123/msgs/422182.html
http://www.dr-bob.org/babble/alter/20041123/msgs/422932.html
save me retyping my opinion ..I'm lazy <g>
Jan
Posted by MKB on December 18, 2004, at 10:02:07
In reply to Re: Tryptophan and B6, posted by sabre on December 18, 2004, at 0:55:09
Tryptophan has worked great for me after the first couple days getting used to it. I'm only taking omega 3 fish oil and a multivitamin, even though I've read you need to take the extra B vitamins. Maybe the extra B vitamins are not that necessary. Just a thought. I would not be able to function without the tryptophan. I was out of it for a few days and I could tell a big difference in the way I was able to handle things.
Posted by Larry Hoover on December 18, 2004, at 10:09:10
In reply to Tryptophan and B6, posted by sabre on December 16, 2004, at 16:58:57
> I tried B6 for the first time yesterday - 240mg.
>
> I also took tryptophan (and Mg) - about 1/3 tsp in the evening. I have tried it a few times and every time I suffered headaches and nausea the next morning. However I had no negative reaction this time. Felt quite good.
>
> It makes me wonder if the reason Lexapro, Moclobemide etc caused problems was due to deficiencies in B6 and Mg?
>
> sabreIt's fine and dandy to take targetted supplements (i.e. ones with specific intended biochemical effect), but you must never take members of the vitamin B family alone. Take the extra vitamin B on top of a B-complex that is roughly proportional to the lone B whose effect you wish to emphasize. Because of the dose of B6 you're suggesting, I would recommend a B-100 supplement.
Lar
Posted by Larry Hoover on December 18, 2004, at 10:12:01
In reply to Re: Tryptophan and B6, posted by sabre on December 18, 2004, at 0:55:09
> Hello TJ
> Thanks for that advice. I was looking at a book called ''Brain Candy'' and they also mentioned there were problems with taking high doses of B6. They said don't go over 100g per day because high doses over time can cause neurotoxicity. Is that your concern too?B6 neuropathy occurs because it induces deficiencies in other B vitamins, while simultaneously reducing the symptoms of those other deficiencies. That's why B-complex vitamin supplements exist. You need to balance your intake.
> I'll ditch the Tryptophan but continue experimenting with a lower dose of B6 and try the B3.
>
> So far only tyrosine and magnesium have done anything....
>
> sabreI do hope that you bought niacinamide. There are different forms of B3, and you only want this specific one.
Lar
Posted by sabre on December 20, 2004, at 3:52:06
In reply to Re: Tryptophan and B6 » sabre, posted by Larry Hoover on December 18, 2004, at 10:12:01
Yes, I did take a B complex with the B6. The reason I took the 240mg dosage was because that was what the message on the bottle recommended.
So many posts recommend various vitamin Bs but the B complex only ever seems to have small amounts of each Vit B. Can you just take extra Vit B Complex and get the same effect?
As for B3..... I bought the nicotinamide (not the niacin. It was a 250mg dose. I ended up feeling more nervous on it. Is my brain matter whacked????
I'm feeling a bit depressed and that this path is futile.
sabre
Posted by gromit on December 20, 2004, at 19:55:56
In reply to Re: Tryptophan and B6 » sabre, posted by Larry Hoover on December 18, 2004, at 10:12:01
> I do hope that you bought niacinamide. There are different forms of B3, and you only want this specific one.
What is the reason you would only want niacinamide?
Thanks
Rick
Posted by Larry Hoover on December 24, 2004, at 16:27:14
In reply to Re: Tryptophan and B6, posted by sabre on December 20, 2004, at 3:52:06
> As for B3..... I bought the nicotinamide (not the niacin. It was a 250mg dose. I ended up feeling more nervous on it. Is my brain matter whacked????
Some people have ultra-rapid enzyme activity, and they convert niacinamide to niacin very quickly. It may not suit you. Another alternative is to try a different brand. Brand shouldn't matter, but it seems that it does.
Lar
Posted by Larry Hoover on December 24, 2004, at 16:28:25
In reply to Re: Tryptophan and B6, posted by gromit on December 20, 2004, at 19:55:56
> > I do hope that you bought niacinamide. There are different forms of B3, and you only want this specific one.
>
> What is the reason you would only want niacinamide?
>
>
> Thanks
> RickI was focussing on the calming, anti-histaminic effect of niacinamide. Niacin (nicotinic acid) is excitatory, and pro-histaminic.
Lar
Posted by gromit on December 26, 2004, at 6:30:31
In reply to Re: Tryptophan and B6 » gromit, posted by Larry Hoover on December 24, 2004, at 16:28:25
> I was focussing on the calming, anti-histaminic effect of niacinamide. Niacin (nicotinic acid) is excitatory, and pro-histaminic.
Ahhh, calming anti-histaminic effect is what I'm trying to avoid! If I were any more calm you might mistake me for a rock or something.
Thanks
Rick
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