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Re: Watch out for next-day Taurine lethargy . » Molitor

Posted by tecknohed on December 2, 2007, at 18:06:26

In reply to Re: Watch out for next-day Taurine lethargy . » tecknohed, posted by Molitor on November 29, 2007, at 9:56:25

> That's good to hear about Marplan. Sounds like it would be worth a try, but I'll have to plan ahead and track down a pharmacy that can get it. I just didn't have the mental/physical energy/motivation to deal with all that before I started the Parnate, even though that sounds like a trivial thing. I guess if I did, I wouldn't need the Parnate in the first place...
>
> I'll be interested to hear how you progress on it. I hope it's not like Nardil, where you end up Chasing the Nardil Dragon trying get back the effects you know it's capable of...

No, not like Nardil's initial effects. Combined with the Klonopin it's anxiolytic effects are just like Nardil's - very powerfull, but theres little or no euphoria like the first few months of Nardil can give.

> Anyway, I take a small scoop (I think it's a 1/3 tsp. I got with something else) of acetyl L-carnitine (ALCAR), 3 times a day. This would be about 500mg per dose, or about 1500mg a day. It might be a little more, because it clumps like slushy snow and doesn't measure like a free powder. I think it absorbs moisture from the air and liquifies, so keep it tightly closed.

Sounds similar to idebenone's texture & with idebenone 1/4 tsp = 420mg. Still, I have digital scales weighing in 0.01g divisions, so when it arrives I'll weigh 1/3 tsp & let you know what it weighs.

> I think it's perfectly reasonable to expect some positive effect from ALCAR. But it's not a Provigil effect, it's more like: "I don't feel nearly as wiped-out today as I did this time last week."

Exactly what I'm hoping for! :)

> I've ordered some propionyl L-carnitine (PLCAR), and I'm going to switch to that to see how it compares to ALCAR. The one study shows they both affect fatigue differently, but are less effective when combined. Here's some PubMed abstracts on ALCAR/PLCAR:
>
> http://tinyurl.com/35dqf7
> http://tinyurl.com/36ozpp
> http://tinyurl.com/33e4wd
> http://tinyurl.com/2vtk7c
>
> As always, you have to be careful about drawing conclusions on physically healthy people from small studies of people with MS or CFS. But at least it's a starting point if you have to experiment on your own. I'll be interested to hear you experiences with it.
>
> -Moli
>

Likewise, let me know how ALCAR & PLCAR compare. And thanks for the links!

teck


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