Posted by tealady on December 7, 2004, at 18:08:55
In reply to Re: dopamine autoreceptor problem » KaraS, posted by raybakes on December 4, 2004, at 13:36:29
>
> As well as opiates, gaba, glutamate and acetylcholine appear to have an effect on presynaptic dopamine receptors - are they the same as autoreceptors?
>Yes, and sure to be others :-)
My guess is that autoreceptors have to be by definition pre-synaptic. In books I just looked up the term seems to be the same.
But I would have thougt that presynaptic receptors could have feedback by other things other than "self" and I get the impression that autoreceptors are receptors in the same synapse that released them..so unsure if autoreceptors are a subset of presynaptic or the one and same term...Autoreceptors can inhibit or facilitate release of neurotransmitters.
Ganong "Review of medical physiology" pp 96 mentions receptorsit says (as one would expect) prolonged exposure to their ligands causes most receptor to become unresponsive..ie to undergo desensitization.
> Just started reading a book called "prozac backlash" It talks about SSRIs inhibiting dopamine, and so dramatically reducing female hormones. I wonder whether autoimmunity increases with SSRIs, what do you think?
>
> Ray
>
Yes Ray, probably all true. I just enjoy tearing up scripts for SSRI's in the past few years..Jan
poster:tealady
thread:413185
URL: http://www.dr-bob.org/babble/alter/20041123/msgs/425839.html