Posted by raybakes on November 3, 2004, at 14:37:55
In reply to Re: Bowel toxins,enzyme peptide conversion of aminos? » raybakes, posted by Larry Hoover on November 2, 2004, at 11:37:57
> A sulphonase has to be different than a sulphatase, though, as the designated substrate is different.
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> A sulphoxide has one oxygen double bonded to sulphur. An example is DMSO (dimethyl sulphoxide; methyl- S=O -methyl). An example of a sulphonyl sulphur is MSM, methyl-sulphonyl-methane. It has a two oxygen atoms, double-bonded to sulphur (methyl- O=S=0 -methyl). A sulphonate sulphur has three oxygens, but a single bond to the organic substrate. A sulphate sulphur is sulphur bound to four oxygens, and is bound to the organic substrate by an oxygen bridge.
Thanks Larry, you certainly give good value!!I'm fascinated by the sulphur thing because I know how much benefit I personally get to my gut and brain when I take MSM - I get similar effects with sulphate, but I don't get loose stools with MSM.
Again in autism they have found that CCK being sulphated helps autistic children, also mucin in the gut needs to be sulphated too.
I also did a search for mucin in the brain and came up with this article about glycoproteins being involved in synaptic transmission...what do you think?
Ray
Glycobiology of the synapse
Paul T. Martin
Department of Neurosciences, Glycobiology Research and Training Center, University of California, San Diego, School of Medicine, 9500 Gilman Drive, La Jolla, CA 92093-0691Abstract
Synapses are the fundamental units of connectivity that link together the nervous system. Lectin studies from 30 years ago suggested that specific glycans are concentrated at neuromuscular synapses in the peripheral nervous system and at excitatory synapses in the brain. Subsequent studies have confirmed that particular glycan structures are localized at these synapses, including polysialic acid, high mannose, the cytotoxic T cell antigen, and forms of heparan sulfate. Though the role of these molecules in synapse formation and function is still poorly understood, there is increasing evidence that the function of agrin, a synaptogenic factor in neuromuscular formation, is modulated by several glycans. In addition, the recent generation of ST8SiaIV null mice strongly suggests a role for polysialic acid in synaptic plasticity in the some regions of the central nervous system.
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poster:raybakes
thread:407758
URL: http://www.dr-bob.org/babble/alter/20041022/msgs/411173.html