Posted by Larry Hoover on July 7, 2004, at 11:32:03
In reply to Re: NADH a psychostimulant?, posted by gromit on July 5, 2004, at 3:39:30
> > I have to resort to anecdote to explain specifics. In my experience, and in that of a "lost" poster, Ron Hill (I miss you, Ron), it takes some time for the NADH effect to build. I liken it to filling up a well. Both Ron and I found that 10 mg/day was needed initially, and that over time the effect seemed to increase. Then, and quite dramatically/suddenly, we both found that 10 mg/day was too much (as if the well filled up, and started to overflow). Thereafter, 5 mg/week was sufficient to maintain the effect. We both found that trimethylglycine (TMG) had a synergistic effect, making the NADH stimulation more pleasant.
> >
>
> That's so weird because I had the exact opposite experience. The first day NADH had an INTENSE effect, the closest thing I can think of would be freebasing cocaine, except the effect lasted 12+ hrs.You don't mention dose, but I'll presume 10 mg?
> When I woke up the next day the stimulation was still there, took another 10 mg and had energy the whole day as well, much less intense though. Probably a good thing.
>
> After those 2 days it seemed to have the opposite effect, almost like a sedative or something and I stopped for a few months. Started it again last week and so far nothing. Maybe I should give it a little longer.Ron and I both felt a mixed reaction, kind of sedative, I suppose, but certainly irritability was a factor. That's the point where we both went to spacing the dose out. I went to 5 mg per week, at the onset of that "threshold" experience.
> I had another experience like this a long time ago from one of those mega packs of vitamins from 7-11. When I tried it the next day it did nothing.There's a lot we don't understand about NADH. I have a chronic fatigue type syndrome, and it has high efficacy in CFS. It would probably help in fibromyalgia. Probably in chronic treatment-resistant depression. It's all a guess, though.
Lar
poster:Larry Hoover
thread:361036
URL: http://www.dr-bob.org/babble/alter/20040613/msgs/363724.html