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Re: Finally trying vortioxetine -- initial impressions undopaminergic

Posted by SLS on December 9, 2022, at 13:10:40

In reply to Finally trying vortioxetine -- initial impressions, posted by undopaminergic on December 9, 2022, at 8:14:21

Hi UD.

One of my many examples of unsolicited advice:

> All in all the trial is off to a good start.

I'm happy to hear that. I'll say a prayer or two for you. Even if there's no God, I don't see how it could hurt.

I hope this stuff helps. I think it is a healthy posture to take. It might bring you closer to discovering a successful, and possibly unique treatment. It should help to optimize your treatment trials in order to search for remission.

1. Just take the pill for a minimum of 4 weeks. If you feel even a mild, but discernible improvement at 4 weeks, go at least 2 more. If not, consider adding adjunctive medications.

2. Stop looking microscopically at how vortioxetine is affecting you day by day - or even hour by hour. You will only obsess - and perhaps abort the trial prematurely. Just take the pill and forget about it. Spend your time doing normal stuff that has nothing to do with your mental illness. Reduce your visits to Psycho-Babble. Doing normal stuff is the only way you can truly evaluate your degree of improvement in mood and function.

3. Increase your brain stimulation frequently by changing your environment and performing varied - and especially novel tasks.

4. Go for walks.

5. Perform 20 minutes of aerobic exercise at least a few days per week. Anaerobic exercise helps too, but only minimally.

6. Don't worry about the pharmacology of vortioxetine. You will only obsess - and perhaps abort the trial prematurely.

7. Take the pills and live your life.

* The only reason to stop taking vortioxetine that I can think of, other than for lack of efficacy, is if significant treatment-emergent adverse events (side-effects) appear that do not show a trend towards dissipating. Don't do *anything* without talking to your doctor first unless there is urgency.

* If you are going to perform any research at all to improve your chances of getting well, change your focus. Spend less time researching pure neuroscience and more time researching the clinical application of psychiatry. Research various treatment modalities, including medication. Study observed phenomena and statistics when treating real people.

* Just take the pills and don't give it another thought unless side effects become problematic.

Good luck!!!

- Scott

Some see things as they are and ask why.
I dream of things that never were and ask why not.

The only thing necessary for the triumph of evil is that good men do nothing.




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