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Re: TRIP8b inhibitors? Truly novel antidepressants. SLS

Posted by bleauberry on April 27, 2018, at 8:51:11

In reply to Re: TRIP8b inhibitors? Truly novel antidepressants. bleauberry, posted by SLS on April 24, 2018, at 18:40:10

> > > I take umbrage to your characterizations of scientists and the state of biological psychiatry.
> > I take umbrage that modern science sentenced me to 20 years in a dungeon despite being an innocent prisoner. I take umbrage that it continues to happen to millions of people like me. The best they can do is throw SSRI's at them. I take umbrage at that.
> >
> > But it is the best we have so we have to work with it. It really doesn't advance the cause for you, me, or anyone else to be feeling umbrage about anything.
> Then don't take umbrage at modern science! That's exactly the point!
> I'm sorry that it took so long for you to get well. This is not the fault of science or scientists.

Of course it is. They are the ones who developed the Lyme lab tests. They are the ones who hide the embarrassingly low accuracy rate of those tests. They are the ones, at the CDC, who direct every other doctor how to interpret those tests. They are the ones who told me, "We are happy to inform you that your test came back negative and you do not have Lyme disease." Look, it wasn't the local grocery or retail or attorney or MD who said that - it was the scientists at the CDC.

>They work hard.

Hard work is not at all the same thing as effective work. Their 'hard work' is well rewarded with salaries and benefits well above the national average. While it is tempting to have this pristine image in the mind of dedicated scientists working hard to bring us cures, it's really not like that. Their goals are not your goals.

>I'm sure people who have Parkinson's or Alzheimer's have a very understandable disappointment - and even anger - aimed at the slow pace of discovery. I think most recognize the value in the scientific method, though.

Show me some facts on that. How many people recognize the value in the scientific method? and what exactly does that mean?It's a nice word salad.

> You say that Lyme Disease is the cause of 9 out of 10 cases of psychiatric symptoms.

No I did not say that. I repeated it. The original 'sayers' were Dr. C LLMD and Dr. D LLMD, both of different states, both who treated me, both who do psychiatry and lyme all day long, nothing else.

>What exactly is the number of cases of Lyme Disease nationwide? Having that number would be instructive.

Nobody knows. That's because diagnosis and testing are so poor. The best estimates by LLMDs are that for every 1 patient who is correctly diagnosed, there are 9 others walking around without a diagnosis or with a wrong diagnosis of some other mystery disease. There are so many people with mystery diseases - fibromyalgia, chronic fatigue, lupus, depression, anxiety, tremors, dementia, Alzheimers, parkinsons, on and on - which can and have improved on antibiotics, including total remissions, including disappearance of brain lesions in MS, when prescribed ABX for some other unrelated reason. This is exactly how LLMDs first noticed the clue that maybe all this stuff was unsuspected lyme instead. Unless you challenge it with antibiotics, you will never know.

> Would one be partially to blame for wasting years of their life were they to swear that the amalgam fillings in their teeth were to blame for their psychiatric symptoms?

Getting amalgam fillings replaced with white composite is one of the first things any chronically ill person should accomplish or they may never get better. Some people go their entire lives healthy, vibrant, bouncy, with amalgam fillings and mercury the whole time. These people have good detox genes. Not every body is that fortunate. Especially in chronic illnesses, we an have inadequate detox genes that allow trace amounts of toxins to accumulate over time into non-trace pathogenic levels. Many mystery disease including psychiatric have been improved or cured with this one procedure. I had half a dozen amalgams removed. I personally felt only minor benefits at best, short term, but I will never know if my current improved state has anything to do with it. I believe everything positive we can do is accumulative in battling disease.Maybe we can't point a finger at any single thing, whether it be a drug, an herb, a procedure, a life style, whatever. It is the whole picture that matters.

>What about focusing on Candida yeast infections?

Candida is a more common health issue than people are aware, in my opinion. It can cause everything from depression to brain fog to fatigue to everything. It can look like Lyme, It can look like psychiatric, it can look like mystery diseases. Battling Candida is part of the anti-lyme protocol. It comes with the territory. There are some effective herbs, but Diflucan works best, and simply removing sugars and starches from your diet can clean it up. There can be huge Herxheimer reactions doing this. Indicating the problem was severe.

>Alternative treatments can be attractive if mainstream medicine has not yet provided a cure. Desperation is a strong motivator.

20+ years not making much progress in psychiatric treatment is the definition of desperate, if you ask me. I also believe that most of what we consider 'alternative' treatments should actually be 'first line' treatments. You save the conventional mainstream treatments for alternative failures, or for serious acute situations. imo. Here is a 'for example' - let's say a patient is referred to a psychiatrist with anxiety, tremors and unexplained fear. There is not a good explanation. Instead of immediately starting the patient on Xanax, why don't we give that patient 5 days of 1-2 antibiotics and 'see what happens'?(assuming the psychiatrist knows his/er stuff and what to look for) It makes a ton more sense than giving the patient 12 weeks of lexapro to 'see what happens'.

> 9 out of 10 psychiatric patients have Lyme Disease? At least now I can eliminate mercury and Candida from consideration. That will be a real time-saver.

Sounds kind of pessimistic in a ridiculing tone. The truth is, we do all of those. If you want to get rid of depression for good, we have to do all of those. It's part of a 'comprehensive' plan that should also include psychiatric meds that help the patient in the short run have a better quality of life while treatment strategies play out. I don't think we can 'restore wellness' without a comprehensive approach. Most of what modern medicine is merely 'managing disease', not restoring wellness. What I love so much about the lyme approach in psychiatry is that it forces the patient to think in a comprehensive way. It covers untold wide spectrum pathogens of bacteria, virus and fungi, inflammations of all kinds, and toxicities. It also includes focused grocery carts and removal of mercury from your teeth. It is my hunch that lyme treatment itself is not the psychiatric cure, but rather, the comprehensive approach of it that is. That said, people have and do get totally better with just ABX.

> You show little or no respect for science, scientists, or psychiatry. You judge everything by an extrapolation of your own experiences. This is not good science. Fortunately, I didn't rip the fillings out of my mouth 10 years ago.

I have great respect for scientists who get it right. Like the ones for example working on space ships to Mars and curing Lyme disease, mining coal, producing energy, sending skyscrapers to the clouds that can bend in hurricanes, etc. Unfortunately much of today's science industry has been corrupted and polluted by profit-seeking, funding-seeking, politics, and greed. They don't suffer. You do. The patient does. I think this happens the most where the lines are blurred, where things are not black and white, for example, in mystery diseases and in psychiatry.

You have mercury in your mouth. Leaching into your body. The 2nd most toxic substance on earth. And it's literally an inch from your brain. Establishment science says that is perfectly safe. Alternative science says absolute not. So choose your team. We can already prove that people do get better with amalgam removal because their stories are all over the world and all over the internet. There are many countries who outlaw amalgams! If you are all about defending science, Scott, then fine, defend how trace amounts of mercury in the body is going to be helpful in any way for a psychiatric patient. Totally makes no sense and doesn't even need any science to figure that out.

> People who are in agony and have not yet found a treatment that relieves them of their frustration and pain become desperate and are willing to try almost anything*.

That is actually not true. My doctors all told me that I was an unusual patient in that I became active in my own recovery and treatment, did my own research, asked tough questions, researched high and low, and I challenged conventional mainstream beliefs due to their widespread disappointments. Most people don't do that. My doctors told me that even when treatment has not been fruitful, the majority of patients prefer status quo - just go to the appointment, get a prescription, and that's it. Even when they land in a wheelchair due to ineffective treatments, they still do not seek out second opinions or other treatments. We see that same phenomenon right here at babble. I get the sense there are patients who would rather stay on the journey they are on, rather than risk their comfort zone or challenge their longhand world views. Many would and do stay sick and refuse to try to copy what has been successful to other people, merely because it challenges longhand patriotism to the science of psychiatry.

>I do not think it is fair to promise a cure by choosing to reject modern medicine in the hope that they will attain wellness by promoting Lyme Disease treatment for 9 out of 10 people.

Suggesting. Not promoting. Awareness. But since you mentioned it, pretty much all psychiatrists give their patients the sense that their prescriptions will help them, cure them, make them feel better. So I agree with you - that is very unfair.

I would just suggest the challenge to show me where I 'promised' anybody anything.

> Personally, I believe that Lyme Disease can produce psychiatric symptoms - and some very severe ones. It's your numbers that don't work.

I don't understand the fixation on things that have nothing to do with furthering the journey of healing. I mean, maybe statistician or data managing would be something interesting for you to do?

>I addressed this in a previous post. Using more liberal numbers, for every 100 people displaying psychiatric symptoms, only one will have Lyme Disease. The more concervative number was 1/338. This value depends upon the number of cases of Lyme Disease occuring nationwide. However, Lyme is not distributed equally throught the US. Many states have almost no cases at all. Yet, your 9/10 does not account for regional differences. If Lyme is not global, how can your one-size-fits-all assertion be global?

The above paragraph is a bunch of myths gathered together. Ticks are in every state. They have been spotted walking on ice in Alaska. They are currently exploding in New England following multiple sub-zero periods during winter. They find their way everywhere on the feathers of birds and the furs of mice. I have personally seen - last year - a tick crawling on snow after a blizzard. I don't think any of the creatures who harbor lyme germs care much about borders or what country they are in. My first tick bite was a German tick. The Asian ones are supposed to be really bad and were just found this year in New Jersey for the first time. Explain that. How did Asian ticks get to New Jersey in 2018?

Recently it was proved that lyme infections survive in sexual fluids and pass to the infant. So that opens up a whole new can of worms much bigger than ticks. There are reports of lyme being spread by mosquitoes and biting flies. I personally did get a bullseye rash around one mosquito bite out of 20. One night I got bit a lot. Ran out of mosquito repellent. One of them developed a bullseye! I have a photo of it.

What this paragraph tells me is that there is strong opposition and resistance to new ideas that challenge old beliefs. There is very little risk, little cost, and yet a huge disproportionate rejection of it. I don't get that kind of resistance. It just tells me my doctors were maybe right - that many patients just want answers, prescriptions, and magic, without doing the comprehensive work to actually get there.

> * I remember when Laetrile/Amygdalin for treating cancer was the cure du jour. People flocked to Mexico in the 1980s to get their hands on it. Unfortunately, consuming aprocot pits proved to be more snake-oil than cure. The scientific method worked to put this question to rest. The National Institutes of Health created in 1993 a department dedicated to the pursuit and testing of Complementary and Alternative Medicine along with Integrative Medicine. This program is grounded in the scientific method.

Never even heard of it.

> - Scott




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