Posted by TriedEveryMedication on October 22, 2016, at 17:39:22
In reply to Re: managing desipramine insomnia - again. - Oops, posted by SLS on October 22, 2016, at 16:19:05
> > So would clonidine be better for insomnia than prazosin?
>
> I don't think prazosin helps with insomnia, except, perhaps, for those people who are afraid to sleep for fear of having a nightmare due to PTSD.
>
> Some people report using clonidine for insomnia. I don't know anyone who has, though. Unfortunately, clonidine tends to be depressogenic, even in people who have never been depressed before. Pharmacologically, it does the opposite of Remeron (mirtazapine) on NE alpha-2 receptors.
>
>
> - ScottWell, anecdotally for me if I take desipramine alone at bedtime, I wake up at 2:30am consistently and can't go back to sleep until 5 or 6am. Even at low doses of desipramine (10mg)
If I take a 1mg prazosin with the desipramine, I sleep through the night.
poster:TriedEveryMedication
thread:1090062
URL: http://www.dr-bob.org/babble/20160928/msgs/1092724.html