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Re: managing desipramine insomnia - again.

Posted by linkadge on July 2, 2016, at 8:32:56

In reply to Re: managing desipramine insomnia - again. » linkadge, posted by TriedEveryMedication on July 1, 2016, at 14:29:17

Hi,

Yes, guanfacine does have the same effect (alpha-2 agonist) which temporarily supresses norepinephrine release and facilitates cholingeric neurotransmission.

You *may* wish to approach the combination of guanfacine + desipramine with doctor supervision. While there is no direct interaction, there could be BP fluctuations depending on doses & timing.

I know guanfacine has been used successfully in combination with Ritalin and / or straterra. There are case reports of cardiac side effects.

Linkadge


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URL: http://www.dr-bob.org/babble/20160609/msgs/1090085.html