Posted by SLS on July 1, 2015, at 14:10:53
In reply to Re: Methylene blue for depression?, posted by SLS on July 1, 2015, at 7:13:45
> > > Hi.
> > >
> > > I'm glad you decided to post.
> > >
> > > I know methylene blue has been used to treat depression. It is not a completely preposterous idea. I have not tried it personally, and I don't know for what type of depression it is best used for.
> > >
> > > Sorry I couldn't help.
> > >
> > >
> > > - Scott
> >
> > MB has been trialed as a treatment for bi-polar depression:
> >
> > Alda, M, Methylene blue for residual symptoms and for cognitive dysfunction in bipolar disorder: results of a double‐blind trial. 2011.
> >
> > In vitro, MB is an extremely potent MAOI. It has been proven beyond reasonable doubt to have been the causative agent in human fatalities linked to serotonin syndrome (induced by the co-administration of SSRIs or SRIs).
> >
> > Instead of going for MB, why not start with a conventional MAOI? What therapeutic advantage does MB have over parnate or nardil? Even if it has a theoretical advantage, you would probably have more success with your doctor by proposing to trial a conventional MAOI before you even think of MB.
> >
> > Good luck.
> >
> > More (very thorough) info:
> >
> > http://www.psychotropical.com/methylene-blue
>
> If the author is accurate in his assays and conclusions, methylene-blue might be the best MAO inhibitor for me. I have had experience with a potent and selective MAO-A inhibitor named clorgyline. To date, clorgyline has been the most potent MAOI drug for me. Unfortunately, this former investigational drug is no longer available for human consumption.I am somewhat disappointed to learn that methylene blue is a reversible rather than irreversible inhibitor of MAO-A.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1080121
URL: http://www.dr-bob.org/babble/20150629/msgs/1080146.html