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Re: Methylene blue for depression? SLS

Posted by Robert_Burton_1621 on July 1, 2015, at 6:28:02

In reply to Re: Methylene blue for depression? pleuraleffusion, posted by SLS on July 1, 2015, at 2:58:30

> Hi.
> I'm glad you decided to post.
> I know methylene blue has been used to treat depression. It is not a completely preposterous idea. I have not tried it personally, and I don't know for what type of depression it is best used for.
> Sorry I couldn't help.
> - Scott

MB has been trialed as a treatment for bi-polar depression:

Alda, M, Methylene blue for residual symptoms and for cognitive dysfunction in bipolar disorder: results of a double‐blind trial. 2011.

In vitro, MB is an extremely potent MAOI. It has been proven beyond reasonable doubt to have been the causative agent in human fatalities linked to serotonin syndrome (induced by the co-administration of SSRIs or SRIs).

Instead of going for MB, why not start with a conventional MAOI? What therapeutic advantage does MB have over parnate or nardil? Even if it has a theoretical advantage, you would probably have more success with your doctor by proposing to trial a conventional MAOI before you even think of MB.

Good luck.

More (very thorough) info:




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