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Methylene blue for depression?

Posted by pleuraleffusion on June 30, 2015, at 20:48:46

Hi, this is a first post but I'm a veteran lurker. At my wits end, hoping I can get some advice, even bad advice is preferred over none. I'm one of those people that is simply so floridly f*ck*d in the head that even my pdoc won't take my money anymore.

I'm psychotically depressed but can't really tolerate antidepressants. Most ADs totally preclude sleep for days, even ADs with low side effect burdens like lamictal and the SSRIs. Hence, I've turned to "alternative" treatments.

I came across this article speculating that "depression is essentially a disease of synaptic wear-and-tear" and that methylene blue can help rescue some of the cognitive deficits associated with depression.

I would love some feedback about whether the aforementioned claims are complete bunk or have a basis in reality.

TLDR: has anyone heard of methylene blue being used to treat depression?




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