Posted by SLS on September 18, 2012, at 10:08:42
In reply to Re: Does exercise make anyone else To Scott, posted by Meltingpot on September 18, 2012, at 8:50:35
Hi Denise.
> Hi Scott,
>
> Rather than the word 'Sweet' I should have used the word 'kind' not 'sweet' (sounds patronising) as you come across as a very kind person in your messages.I wasn't offended in the least. Coming from you, it never entererd my mind that you had meant anything other than good things. I think your calling me sweet is very sweet.
:-)
> Also, you always seem to be very dilligent and methodical when it comes to taking medication.
Not always. I can be patient if I think something has a chance of working, but become very impatient when I am convinced otherwise. After 30 years, I have come to appreciate the time it sometimes takes for positive changes to occur.
I don't see Nardil.
Effexor - what dosage and for how long? You might want to use an anxiolytic drug like Zyprexa or Klonipin temporarily while the Effexor "settles in". For you, I guess Zyprexa makes the most sense. For depression and GAD, I would say that one would want to go up to at least 300 mg/day of Effexor. If Pristiq is available, I would use that instead of Effexor. I think it may be more tolerable and more effective. However, I am dubious about the low dosages that are usually prescribed. You would want to go up to 100 mg/day as rapidly as you can tolerate. I am suspicious that higher dosages are required for many people, but the drug company doesn't want to recommend higher dosages because they assume it would be less appealing to practicioners if side effect load is increase. However, I don't think this has been observed in clinical trials. 400 mg/day seems to be tolerable.
http://www.ncbi.nlm.nih.gov/pubmed/22883315
What dosage of clomipramine did you take?
I will be interested to see what the trimipramine does for you. I tried it and did not experience any sedation at all from it.
If you have not tried Nardil yet, I think you might be missing out on an opportunity to feel well. Even Parnate might be worth a try. You would have to discontinue the Seroxat, though. You can add nortriptyline to a MAOI, but not imipramine or clomipramine.
If you haven't added a noradrenergic TCA to Seroxat, I would consider it. Trimipramine doesn't count. Nortriptyline or desipramine are preferable. Because there is a pharmacokinetic interaction between these drugs, you must take only 1/2 the dosage of TCA normally used when combined with Seroxat. This might be true of trimipramine as well. If this interaction has not been addressed by your doctor, you will need to have a conversation with him about this. You don't want to become toxic on trimipramine. You should probably start with 25 mg/day and move to 50 - 75 mg/day.
- Scott
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> To answer you question. Here is the list of medication I have tried.
>
> Prozac and doxepin
> Mirtazapine - More anxious, still depressed.
> Effexor - Anxious
> Lamictal - Didn't seem to do anything.
> Lithium and sertraline - Slightly better.
> Seroxat 40mg - felt much better for about two years and then the anxiety came back.
> Seroxat and Mirazapine - Slightly better, still not right.
> Seroxat and Thyroid hormone = No change
> Seroxat and Lithium - No change.
> Escitalopram - was ok on it for about two years, not exactly well but not in the pits. This lasted two years and then the anxiety came back.
> Seroxat and tryptophan - no change
> Zyprexa - Always helps but feel sort of flat on it at times.
> Seroxat and abilify - No change
> Clomipramine - less anxiety after intial anxiety up to 5 weeks.
> Wellbutrin - Make me more drowsy.
> Klonopin (occasionally) does actually help but don't want to keep taking it and then become addicted to it, like some people seem to have been.
Some see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1023256
URL: http://www.dr-bob.org/babble/20120912/msgs/1026028.html