Posted by Beckett on April 12, 2012, at 9:15:23
In reply to Re: Saphris/asenapine » Beckett, posted by tensor on April 11, 2012, at 13:51:14
> > > Is Saphris worth trying for treatment-resistant unipolar depression? I haven't done well on other AAPs.
> How are the side effects? How do they compare to the other AAPs?
In my experience, Saphris is sedating, and I need to watch the dose because too much will over-flatten me. It is not brightening like Abilify, but I did not tolerate Abilify nor Latuda. I found both to be agitating. I am treating some kind of depression that has a cyclic nature to it, likely bipolar of some sort. I've corresponded with a couple of people successfully treating schizoaffective disorder with Saphris. Thinking back, I felt the onset fairly quickly, that is, I felt something positive from the beginning, however it took weeks for that to settle into more reliable positive change. Hope this helps....