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Re: Opiates, oxycodone undopaminergic

Posted by Crotale on July 4, 2008, at 8:49:42

In reply to Re: Opiates, oxycodone, posted by undopaminergic on June 27, 2008, at 17:36:33

> It appears that higer doses than about 4 mg of buprenorphine yield little additional benefit, except for more effective blockade of the actions of other opioids such as heroin - this is one of the reasons why it is used as substitution therapy for addicts. For depression and pain, in all cases I've seen described, there seems to be little reason to exceed 4 mg.

I take approximately 0.2mg (0.7cc Buprenex). I would think a dose anywhere near 4mg would make me sick to my stomach! I can't imagine how anyone can tolerate such a high dose, other than drug addicts.




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