Posted by zeugma on October 31, 2006, at 17:26:32
In reply to Re: effect of melatonin on seratonin? » zeugma, posted by linkadge on October 31, 2006, at 6:36:26
> >leading to phase delays in the sleep/wake cycle
> >(specifically, late-sleep/late-wake periods >relative to normal diurnal rhytms).
>
> I'm confused, does normal melatonin administration have this effect?>>
Melatonin administration will produce phase changes in your sleep cycle, depending on when you take it.Since melatonin release in the non-sleep-wake-cycle-disordered person is designed to promote a normal sleep cycle (e.g. sleep from say 11 pm to 7 am) and pharmaceutical administration of melatonin is designed to mimic this effect, if you took melatonin to produce phase advance (ie. to wake up earlier and go to sleep earlier) you would take melatonin in the evening. It seems melatonin release is designed to be highest 12 hours after the exposure to light (about 6-8 p.m.). So melatonin at night makes you somewhat drowsy.
Luvox on the other hand causes melatonin levels to lose their relationship with the diurnal cycle, because the amounts are continuously high. It induces, in other words, a constant feeling of twilight drowsiness. Not in all patients, of course.
-z
>
> Linkadge
poster:zeugma
thread:699037
URL: http://www.dr-bob.org/babble/20061028/msgs/699395.html