Posted by zeugma on October 31, 2006, at 5:18:07
In reply to Re: effect of melatonin on seratonin? » iforgotmypassword, posted by johnnyj on October 30, 2006, at 21:20:55
> If I do start luvox I pray it helps me sleep. How does one know if it is the typical increased anxiety upon starting an ssri or akithisia? Or does one have increased anxiety but still have sedation? This would be good info for me to know if I decide to go that route.
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> I will also need something to tame by bruxism which can become worse with an ssri? maybe neurotonin or buspar??>>Luvox interferes with circadian rhythms, not sleep per se. this refers to the synchronization of sleep-wake periods with the 24-hour diurnal rhythm. The mechanism is purported to be the elevation in plasma melatonin induced by Luvox, which is not a serotonin-mediated effect as other SSR's do not have this specific effect, but rather due to the inhibition of melatonin metabolism in the body, leading to phase delays in the sleep/wake cycle (specifically, late-sleep/late-wake periods relative to normal diurnal rhytms).
I will write more on this when I get back from work, must run now.
-z
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> johnnyj
poster:zeugma
thread:699037
URL: http://www.dr-bob.org/babble/20061028/msgs/699236.html