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Re: Coreg (carvedilol) mike99

Posted by Chairman_MAO on March 7, 2006, at 15:19:27

In reply to Re: Coreg (carvedilol) ed_uk, posted by mike99 on March 4, 2006, at 15:54:11

The best strategy for mitigating cardiovascular toxicity is to use equivalent doses of methamphetamine which has a much higher ratio of CNS:peripheral effects. That is, you can produce significant CNS effects with d-methamphetamine (not dl-meth, which is what most street speed is at best!) with negligable cardiovascular effects. This is not usually possible with d-amphetamine (though d-amphetamine is better than the racemic or Adderall).

A more direct solution to this problem would be low-dose clonidine--this directly reduces sympathetic outflow.




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